Acute Hepatitis by Bartonella henselae Infection in an Adult Patient with Decompensated Liver Cirrhosis

Main Article Content

Jorge Alonso Garay-Ortega
Louis Fernando Robles Fernandes
Vianey Guadalupe Téllez Bolaños
Karla Paulina Sandoval Mosqueda
Karla Daniela Salgado Guizar


adult, Bartonella, gastroenterology, hepatitis, hepatology


Hepatitis caused by Bartonella henselae in adults is a condition that is seldom reported in the literature, as well as its current incidence and prevalence. While there is a broad spectrum of well-defined and established clinical entities, hepatic involvement represents the third most frequent clinical manifestation of infection by this genus of bacteria. It may or may not be characterized by the presence of hepatosplenic granulomas. Diagnosis requires a high level of clinical suspicion, exclusion of additional etiologies, and a causal relationship with risk factors. Polymerase chain reaction is the diagnostic test with the highest diagnostic yield, and treatment varies depending on the clinical expression. We describe the case of an adult patient with hepatitis secondary to Bartonella henselae infection.


Download data is not yet available.
Abstract 67 | PDF Downloads 30 HTML Downloads 9 XML Downloads 5


1. Ramón Blanco J, Raoult D. Enfermedades producidas por Bartonella spp. Diseases produced by Bartonella. Enferm Infecc Microbiol Clín. 2005;23(5):313–20. 10.1157/13074971

2. Nelson CA, Moore AR, Perea AE, Mead PS. Cat scratch disease: U.S. clinicians’ experience and knowledge. Zoonoses Public Health. 2018;65(1):67–73. 10.1111/zph.12368

3. Guerrero-Becerra M, de León-Herrera SR, Plascencia-Hernández A, Mercado-Uribe MC, Martínez-Arce P, Luévanos-Velázquez A, et al. Enfermedad por arañazo de gato (EAG), experiencia del Hospital Civil de Guadalajara (HCG), México. Bol Clin Hosp Infant Edo Son. 2018;35(1):61–9.

4. Rostad CA, McElroy AK, Hilinski JA, Thompson MP, Drew CP, Denison AM, et al. Bartonella henselae-mediated disease in solid organ transplant recipients: Two pediatric cases and a literature review. Transpl Infect Dis. 2012;14(5):E71–81. 10.1111/j.1399-3062.2012.00774.x

5. VanderHeyden TR, Yong SL, Breitschwerdt EB, Maggi RG, Mihalik AR, Parada JP, et al. Granulomatous hepatitis due to Bartonella henselae infection in an immunocompetent patient. BMC Infect Dis. 2012;12:17. 10.1186/1471-2334-12-17

6. Opavsky MA. Cat scratch disease: The story continues. Can J Infect Dis. 1997;8(1):43–9. 10.1155/1997/982908

7. Prutsky G, Domecq JP, Mori L, Bebko S, Matzumura M, Sabouni A, et al. Treatment outcomes of human bartonellosis: A systematic review and meta-analysis. Int J Infect Dis. 2013;17(10):e811–19. 10.1016/j.ijid.2013.02.016

Most read articles by the same author(s)