The Effect of Clinical and Demographic Factors on Quality of Life in End-Stage Renal Disease. A Multicenter Cross-Sectional Study
Main Article Content
Keywords
clinical factors, demographic factors, end-stage renal disease, hemodialysis, quality of life
Abstract
The aim of this study was to assess the quality of life (QoL) in end-stage renal disease (ESRD) patients undergoing hemodialysis and to examine the clinical and demographic attributes associated with it. This is a multicenter, cross-sectional study, conducted in 2018, in which 367 patients with ESRD undergoing hemodialysis were recruited. Data were collected through a two-part anonymous, self-completed questionnaire. The first part contained questions regarding demographic, social, and clinical information, and the Greek version of Missoula–Vitas Quality of Life Index-15 (MVQoL-15) scale was used to assess QoL. Descriptive and inferential statistical methods were applied. All reported p-values were two-tailed, and the statistical significance level was set at 0.05. Of the study participants, 62.1% were male, with a mean age of 61.80 ±15.11. Of the participants, 67.3% were living in urban areas and 59.1% were married. The majority of the Hemodialysis (HD) patients evaluated possessively all the domains of MVQoL except the wellbeing Domain. QoL was found to be influenced, among others, by age (0.001), occupation (0.002), education (0.003), and additional health problems (<0.001). The role of patient characteristics in QoL is an area of interest, and early and proper intervention is important to enhance QoL.
References
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24. Saffari M, Pakpour A, Naderi M, Koenig H, Baldacchino D, Piper C. Spiritual coping, religiosity and quality of life: A study on Muslim patients undergoing haemodialysis. Nephrology. 2013;18(4):269–75. https://doi.org/10.1111/nep.12041
25. Parvan K, lakdizaji S, Roshangar F, Mostofi M. Quality of sleep and its relationship to quality of life in hemodialysis patients. J Caring Sci. 2013;2(4):295–304. https://doi.org/10.5681/jcs.2013.035
26. Minos Ch, Rekleiti M, Saridi M, Filippopoulou T, Tzitzikos G, Souliotis K, et al. Factors affecting quality of life in end-stage renal disease patients on hemodialysis. Hellenic J Nurs Sci. 2012;5(2):64–71.
27. Mandoorah QM, Shaheen FA, Mandoora SM, Bawazi SA, Alshohaib SS. Impact of demographic and comorbid conditions on quality of life of hemodialysis patients: A cross-sectional study. Saudi J Kidney Dis Transplant. 2014;5(2):432. https://doi.org/10.4103/1319-2442.128613
28. Valderrábano F, Jofre R, López-Gómez J. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38(3):443–64. https://doi.org/10.1053/ajkd.2001.26824
29. Yong DS, Kwok AO, Wong DM, Suen MH, Chen WT, Tse DM. Symptom burden and quality of life in end-stage renal disease: A study of 179 patients on dialysis and palliative care. Palliat Med. 2009;23(2):111–19. https://doi.org/10.1177/0269216308101099
30. Alshammari B, Noble H, McAneney H, O’Halloran P. An exploration of symptom burden and its management, in Saudi Arabian patients receiving haemodialysis, and their caregivers: A mixed-methods study protocol. BMC Nephrol. 2019;20(1):250. https://doi.org/10.1186/s12882-019-1424-9
2. Zazzeroni L, Pasquinelli G, Nanni E, Cremonini V, Rubbi I. Comparison of quality of life in patients undergoing hemodialysis and peritoneal dialysis: A systematic review and meta-analysis. Kidney Blood Pres Res. 2017;42(4):717–27. https://doi.org/10.1159/000484115
3. Bello AK, Levin A, Lunney M. Global Kidney Health Atlas: A report by the International Society of Nephrology on the global burden of end-stage kidney disease and capacity for kidney replacement therapy and conservative care across world countries and regions. Brussels: International Society of Nephrology; 2019.
4. Karimi M, Brazie J. Health, health-related quality of life, and quality of life: What is the difference? PharmacoEconomics. 2016;34(7):645–9. https://doi.org/10.1007/s40273-016-0389-9
5. Gotay CC, Korn EL, McCabe MS, Moore TD, Cheson BD. Quality-of-life assessment in cancer treatment protocols: Research issues in protocol development. J Natl Cancer Inst. 1992;84:575–9. https://doi.org/10.1093/jnci/84.8.575
6. Schipper H, Clinch J. Assessment of treatment of cancer. In: Smith GT, editor. Measuring health: A practical approach. New York, NY: John Wiley & Sons; 1988.
7. Theofilou P. Quality of life, mental health and health beliefs: Comparison between haemodialysis and peritoneal dialysis patients. Interscientific Health Care. 2010;2(4):171–6.
8. Heidenheim AP, Muirhead N, Moist L, Lindsay RM. Patient quality of life on quotidian hemodialysis. Am J Kidney Dis. 2003;42:36–41. https://doi.org/10.1016/S0272-6386(03)00536-5
9. Theofilou T, Panagiotaki H. Factors influencing the quality of life of individuals with end-stage renal disease. Nosileftiki. 2010;49(2):174–81.
10. Ginieri-Coccossis M, Theofilou P, Synodinou C, Tomaras V, Soldatos C. Quality of life, mental health and health beliefs in haemodialysis and peritoneal dialysis patients: Investigating differences in early and later years of current treatment. BMC Nephrol. 2008;9:14. https://doi.org/10.1186/1471-2369-9-14
11. Leung KCD. Psychosocial aspects in renal patients. Perit Dial Int. 2003;23(S2): S90–4. https://doi.org/10.1177/089686080302302s19
12. Theofilou P, Aroni A, Ralli M, Gouzou M, Zyga S. Measuring health: Related quality of life in hemodialysis patients. Psychometric properties of the Missoula-VITAS Quality of Life Index (MVQOLI-15) in Greece. Health Psych Res. 2013;1(2):e17. https://doi.org/10.4081/hpr.2013.1004
13. Anees M, Malik MR, Abbasi T, Nasir Z, Hussain Y, Ibrahim M. Demographic factors affecting quality of life of hemodialysis patients—Lahore, Pakistan. Pakistan J Med Sci. 2014;30(5):1123–7. https://doi.org/10.12669/pjms.305.5239
14. Gerasimoula K, Lefkothea L, Maria L, Victoria A, Paraskevi T, Maria P. Quality of life in hemodialysis patients. Mater Sociomed. 2015;27(5):305–9. https://doi.org/10.5455/msm.2015.27.305-309
15. Zyga S. Chronic kidney disease and quality of life. Athens: Beta Publishing; 2017.
16. Santos P, Daher E, Silva G, Libório A, Kerr L. Quality of life assessment among haemodialysis patients in a single centre: A 2-year follow-up. Qual Life Res. 2009;18(5):541–6. https://doi.org/10.1007/s11136-009-9474-2
17. Mujais SK, Story K, Brouillette J, Takano T, Soroka S, Franek C et al. Health-related quality of life in CKD patients: Correlates and evolution over time. Clin J Am Soc Nephrol. 2009;4(8):1293–301. https://doi.org/10.2215/CJN.05541008
18. Hosny G, Kamil LA, Foda N. Assessment of quality of life for hemodialysis patients in Iraq. Int J Environ Sci Toxicol Res. 2017;5(1):10–22.
19. Abdelghany MA, Elgohary EE, Nienaa YA. Assessment of health-related quality of life in patients receiving regular hemodialysis. J Nephrol Ther. 2016;6:246. https://doi.org/10.4172/2161-0959.1000246
20. Tel H. Determining quality of life and sleep in hemodialysis patients. Dial Transplant. 2009;38(6):210–15. https://doi.org/10.1002/dat.20296
21. Zhou X, Xue F, Wang H, Qiao Y, Liu G, Huang L. et al. The quality of life and associated factors in patients on maintenance hemodialysis—A multicenter study in Shanxi province. Ren Fail. 2017;39(1):707–11. https://doi.org/10.1080/0886022x.2017.1398095
22. Bayoumi M, Al Wakeel J, Mishkiry A, Al Harbi A, Al Suwaida A, Al Ghonaim M. Predictors of quality of life in hemodialysis patients. Saudi J Kidney Dis Transplant. 2012;24(2):254. https://doi.org/10.4103/1319-2442.109566
23. Yang S, Kuo P, Wang J, Lin M, Su S. Quality of life and its determinants of hemodialysis patients in Taiwan measured with WHOQOL-BREF (TW). Am J Kidney Dis. 2005;46(4):635–41. https://doi.org/10.1053/j.ajkd.2005.06.015
24. Saffari M, Pakpour A, Naderi M, Koenig H, Baldacchino D, Piper C. Spiritual coping, religiosity and quality of life: A study on Muslim patients undergoing haemodialysis. Nephrology. 2013;18(4):269–75. https://doi.org/10.1111/nep.12041
25. Parvan K, lakdizaji S, Roshangar F, Mostofi M. Quality of sleep and its relationship to quality of life in hemodialysis patients. J Caring Sci. 2013;2(4):295–304. https://doi.org/10.5681/jcs.2013.035
26. Minos Ch, Rekleiti M, Saridi M, Filippopoulou T, Tzitzikos G, Souliotis K, et al. Factors affecting quality of life in end-stage renal disease patients on hemodialysis. Hellenic J Nurs Sci. 2012;5(2):64–71.
27. Mandoorah QM, Shaheen FA, Mandoora SM, Bawazi SA, Alshohaib SS. Impact of demographic and comorbid conditions on quality of life of hemodialysis patients: A cross-sectional study. Saudi J Kidney Dis Transplant. 2014;5(2):432. https://doi.org/10.4103/1319-2442.128613
28. Valderrábano F, Jofre R, López-Gómez J. Quality of life in end-stage renal disease patients. Am J Kidney Dis. 2001;38(3):443–64. https://doi.org/10.1053/ajkd.2001.26824
29. Yong DS, Kwok AO, Wong DM, Suen MH, Chen WT, Tse DM. Symptom burden and quality of life in end-stage renal disease: A study of 179 patients on dialysis and palliative care. Palliat Med. 2009;23(2):111–19. https://doi.org/10.1177/0269216308101099
30. Alshammari B, Noble H, McAneney H, O’Halloran P. An exploration of symptom burden and its management, in Saudi Arabian patients receiving haemodialysis, and their caregivers: A mixed-methods study protocol. BMC Nephrol. 2019;20(1):250. https://doi.org/10.1186/s12882-019-1424-9
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May 7, 2020
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The Effect of Clinical and Demographic Factors on Quality of Life in End-Stage Renal Disease. A Multicenter Cross-Sectional Study. (2020). Journal of Renal and Hepatic Disorders, 4(1), 1-9. https://doi.org/10.15586/jrenhep.2020.58
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Original Articles Nephrology
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